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Table 1

From: Quantitation of cyclic nucleotides in mammalian cells and in human urine by high-performance liquid chromatography/mass spectrometry

cNMP content (pmol/106 cells)

Cell type

Lineage

cAMP

cGMP

cCMP

cUMP

HeLA

epithelial cells

2.1

± 0.5

1.5

± 0.5

0.3

± 0.1

0.7

± 0.3

HL-60

myeloid cells

7.0

± 1.4

0.3

± 0.1

0.1

± 0.03

0.3

± 0.03

J774

macrophages

11.0

± 1.6

1.2

± 0.1

0.5

± 0.02

1.2

± 0.1

CHO

epithelial cells

33.3

± 4.0

10.2

± 1.3

8.0

± 1.6

6.7

± 1.8

B103

neuroblastoma cells

55.1

± 7.3

7.5

± 0.8

14.4

± 1.5

22.3

± 2.8

COS-7

fibroblasts

82.2

± 11.3

52.1

± 3.1

16.3

± 1.7

25.1

± 2.2

HEK 293

epithelial cells

106.5

± 11.3

73.3

± 5.2

32.6

± 6.2

54.9

± 11.3