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Figure 2 | BMC Pharmacology

Figure 2

From: Characterization of mice with a deletion of protein kinase G type I in cardiomyocytes and the effect on cardioprotection through either postconditioning or mitochondria-targeted S-nitrosothiol

Figure 2

Results of open chest experiments. As expected, either IPost, activation of sGC with BAY58 or A2BAR activation with BAY60 resulted in a profound decrease of infarct size in CMG-CTR. While BAY58 failed to protect in the CMG-KO animals, IPost, BAY60, and MitoSNO still afforded protection, suggesting a signaling independent on cGKI in the cardiomyocyte. *p<0.05 vs. control.

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BMC Pharmacology

ISSN: 1471-2210