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Figure 2 | BMC Pharmacology

Figure 2

From: Towards the development of novel Trypanosoma brucei RNA editing ligase 1 inhibitors

Figure 2

The core of the two ligands listed in Table 2, as well as ATP, shown in detail. The ligand poses of the novel compounds correspond to those of the lowest-energy AutoDock clusters; the ATP pose shown is crystallographic. A portion of the protein has been cut away to allow visualization of interactions deep in the Tb REL1 binding pocket. Selected hydrogen bonds are represented by black lines. Only polar hydrogen atoms are displayed.

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