Figure 2From: Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB1) Receptor AntagonistFunctional properties of CE-178253 in GTPγ[35S] binding assays. Panel A. Effect of CE-178253 (0.01 nM-10 μM) on CP-55940 stimulated GTPγ[35S] binding. Panel B. Inverse agonist assay. Panel C. Schild analysis. Panel D. Inhibition of CP-55940 stimulated GTPγ[35S] binding by CE-178253.Back to article page