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Figure 2 | BMC Pharmacology

Figure 2

From: An evaluation of R2 as an inadequate measure for nonlinear models in pharmacological and biochemical research: a Monte Carlo approach

Figure 2

Performance of the nine different sigmoidal models on the fitted values from a three-parameter log-logistic model. (A) The nine different sigmoidal models were fit by nonlinear least-squares to the fitted data from the L3 model. (B) Residual plot depicting the performance of each of the nine models in respect to fitting to the data from the L3 model. As expected, model L3 (light green, reference curve) has zero residual value as having been fit to the data obtained from the same model. Several other models also fit the data exceptionally well (L5, L4, baro5) and are not visible due to being overlayed by the L3 curve. Descriptions for the abbreviated models can be found under Formulas 1-9.

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