Figure 3From: Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?A rational promiscuity approach to drug screening. Coverage maps are generated for individual drugs, here plotted as relative affinity for targets A-J indicated by radial distance from the origin (in arbitrary units). Combining the maps clearly illustrates that targets A-F are shared by all 3 drugs (dotted line). Subsequent screening algorithms would enrich for targets A-F, while avoiding non-shared targets G-J.Back to article page