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Table 2 Effect of natansnin on levels of serum enzymes induced by CCl4

From: Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl4 induced oxidative stress and cellular degeneration in rat liver

 

ALT (IU/L)

ALP(IU/L)

Control

100

100

CCl4

238.26 ± 22.2a

244.82 ± 18.6a

Natansnin (20 mg/kg body wt)

108.26 ± 11.7

114.13 ± 10.9

Natansnin 10 mg + CCl4

173.45 ± 16.2a, b

162.27 ± 14.5a, b

Natansnin 20 mg + CCl4

165.61 ± 15.3a, b, c

145.61 ± 13.6a, b, c

  1. Effect of CCl4 with or without prior administration of natansnin on levels of serum enzymes in liver. Values are expressed as percent response compared to control rats. The control values of ALT and ALP were 53.43 ± 3.6, 285.28 ± 18.2 IU/L respectively. a = Statistical significant at P < 0.05 as compare to control, b = Statistical significant at P < 0.05 as compare to CCl4, c = Statistical significant at P < 0.05 as compare to natansnin (10 mg) + CCl4.
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BMC Pharmacology

ISSN: 1471-2210