TY - JOUR AU - Spindola, Humberto M. AU - Servat, Leila AU - Denny, Carina AU - Rodrigues, Rodney AF AU - Eberlin, Marcos N. AU - Cabral, Elaine AU - Sousa, Ilza MO AU - Tamashiro, Jorge Y. AU - Carvalho, João E. AU - Foglio, Mary A. PY - 2010 DA - 2010/01/07 TI - Antinociceptive effect of geranylgeraniol and 6α,7β-dihydroxyvouacapan-17β-oate methyl ester isolated from Pterodon pubescens Benth JO - BMC Pharmacology SP - 1 VL - 10 IS - 1 AB - Pterodon pubescens Benth seeds are commercially available in the Brazilian medicinal plant street market. The crude alcoholic extracts of this plant are used in folk medicine as anti-inflammatory, analgesic, and anti-rheumatic preparations. The aim of this study was to evaluate the contribution of geranylgeraniol (C1) and 6α, 7β-dihydroxyvouacapan-17β-oate methyl ester (C2) isolated from Pterodon pubescens Benth. to the antinociceptive activity of the crude extract. SN - 1471-2210 UR - https://doi.org/10.1186/1471-2210-10-1 DO - 10.1186/1471-2210-10-1 ID - Spindola2010 ER -