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Figure 3 | BMC Pharmacology

Figure 3

From: Receptorphin: A conserved peptide derived from the sequence of the opioid receptor, with opioid displacement activity and potent antiproliferative actions in tumor cells

Figure 3

Competition of receptorphin action by general and selective opioid antagonists in T47D cells. T47D cells were plated at an initial density of 20000 cells/well, and the effect of the peptide (changed every day) was assayed after two cell cycles (4th day). The number of cells therefore, in control conditions (in the absence of the peptide) was 80000/well. Cell viability was in all cases >95%. Diprenorphin (A) or NorBNI (B) were added simultaneously with receptorphin, at a concentration of 10-6 M. Mean ± SEM of three different experiments performed in triplicate.

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BMC Pharmacology

ISSN: 1471-2210