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Figure 6 | BMC Pharmacology

Figure 6

From: Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia

Figure 6

The time-dependent effect of LPS and Domoic acid on neonatal rat brain microglia TNF-α release. Neonatal rat brain microglia (2.8–5 × 106 cells/culture dish) were treated with Domoic acid [1 mM] or LPS [10 ng/mL] for 1–6 hours. TNF-α was determined as described under Materials and Methods. Data (pg/mL) are expressed as mean ± SE of 2 independent experiments. **p < 0.01 vs. vehicle control.

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