Table 2 Effects of cumulative doses of olanzapine on urodynamic and EMG parameters in anesthetized rats. Values are Mean ± S.E.M.

Control

0.28

0.20

26

4.1

14.3

16.8

2.6

1.6

100

100

100

100

(±0.046)

(±0.037)

(±8.7)

(±0.93)

(±1.26)

(±0.61)

(±0.55)

(±0.19)

0.01

0.30

0.22

23

5.5

13.6

17.0

3.3

1.6

80

138

94 (±4.6)

105

(±0.049)

(±0.045)

(±10.8)

(±0.96)

(±0.90)

(±1.57)

(±0.63)

(±0.17)

(±14.0)

(±23.4)

(±3.2)

0.1

0.39

0.08 ^*

76 ^**

4.9

14.6

17.1

0.9 ^**

1.0 ^*

76 ^*

42 ^**

69 ^**

72

(±0.064)

(±0.014)

(±5.3)

(±1.52)

(±0.91)

(±0.91)

(±0.38)

(±.42)

(±1.9)

(±11.4)

(±12.6)

(±19.2)

1

0.38

0.04 ^**

89 ^**

6.84

12.7

17.38

0 ^**

0 ^**

47 ^**

0 ^**

35 ^**

0 ^**

(±0.072)

(±0.006)

(±2.4)

(±1.79)

(±1.24)

(±2.60)

(±6.0)

(±5.2)