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Figure 5 | BMC Pharmacology

Figure 5

From: Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the urinary bladder and the external urethral sphincter in anesthetized rats

Figure 5

Effects of cumulative doses of olanzapine and risperidone on contraction time, expulsion time and the amplitude of the high frequency oscillations. A) Neither olanzapine nor risperidone significantly changed the contraction time. B) The expulsion time was significantly decreased by both olanzapine and risperidone. Olanzapine abolished the expulsion time at 1.0 mg/kg. C) The amplitude of the HFO was significantly decreased by both olanzapine and risperidone. Olanzanpine had a greater effect, abolishing the HFO at 1.0 mg/kg, whereas risperidone decreased the amplitude to approximately 50% of control values. * = p < 0.05; ** = p < 0.01

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BMC Pharmacology

ISSN: 1471-2210