From: Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels
Treatment
ATP (pmole/islet)
Pa)
none (with ethanolb))
0.72 ± 0.07 (n = 13)
PMA (80 nM)c)
0.75 ± 0.10(n = 13)
>0.05
none (without ethanol)
0.68 ± 0.08 (n = 8)
NaCN (I mM)d)
0.31 ± 0.04 (n = 8)
<0.01