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Table 1 ATP concentration of rat islets after loading with PMA or NaCN

From: Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels

Treatment

ATP (pmole/islet)

Pa)

none (with ethanolb))

0.72 ± 0.07 (n = 13)

 

PMA (80 nM)c)

0.75 ± 0.10(n = 13)

>0.05

none (without ethanol)

0.68 ± 0.08 (n = 8)

 

NaCN (I mM)d)

0.31 ± 0.04 (n = 8)

<0.01

  1. a)P value, compared with the value of the paired control (none). b)The concentration of ethanol was 0.01%. c)PMA was applied for 10 min. d)NaCN was applied for 10 min. All measurements were performed at 37°C.