Skip to main content

Table 4 Theoretical CNBr fragments of the α1-subunit of the sGC. MW: molecular weight; AA: amino acid; the several amino acids are shown in the one-letter-code.

From: NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272

CNBr fragment

MW [kDa]

AA number

AA position in the α1 subunit

Sequence from the N-terminus

CNBr-1

24

215

21–235

APGQVPTEPIEE...

CNBr -2

6.2

54

236–290

PPCFRSECTEFV...

CNBr -3

5.5

47

291–338

LDRDLAILQLG...

CNBr -4

0.2

2

339–340

TM

CNBr -5

0.3

3

341–343

LNM

CNBr -6

2.5

19

344–363

QFVIRVRRWDNL...

CNBr -7

0.6

6

364–369

DLKGQM

CNBr -8

12.5

111

370–481

IYIVESSAILFLG...

CNBr -9

2.4

22

482–504

LFSDIVGFTAICS...

CNBr -10

5.2

46

505–551

LNALYTRFDQQ...

CNBr -11

0.4

4

552–555

ALKM

CNBr -12

0.1

1

556

M

CNBr -13

0.8

7

557–563

ELSNEVM

CNBr -14

0.9

9

564–572

SPHGEPIKM

CNBr -15

1.8

17

573–590

RIGLHSGSVFAG...

CNBr -16

11.2

99

591–690

PRYCLFGNNVT...