BMC Pharmacology

Table 3 Statistical analysis for AUC_0-t(last), AUC_0-∞ and C_max

From: Bioequivalence study of three ibuprofen formulations after single dose administration in healthy volunteers

Parameter	Ratio	Estimate	90%CI
AUC_0-t(last)	E/A	1.0241	0.9959; 1.0531
	E/B	1.0058	0.9700; 1.0430
AUC_0-∞	E/A	1.0240	0.9958; 1.0529
	E/B	1.0060	0.9704; 1.0430
C_max	E/A	1.1084	1.0542; 1.1852
	E/B	1.1732	1.1058; 1.2447
Parameter	Difference	Estimate	90%CI
t_max	E – A	-0.6250	-0.8750; -0.3750
	E – B	-0.6875	-1.000; -0.3750

Statistical analysis by treatment pair (parametric analysis, pharmacokinetic population; N = 60). "A" refers to Nurofen^® forte, "B" refers to Migränin^® and "E" refers to Eudorlin^® extra. CI: confidence interval.

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