From: Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans
Trial | Concentration (μM) | Mean lifespan (days) | Relative survival (%) | p(Logrank) | n (failed, censor) | |
---|---|---|---|---|---|---|
 |  | Treated | Control |  |  |  |
Resveratrol-trimethylether | ||||||
1 | 100 | 9.7 | 12.16 | 80% | 0.004 | 61,0 |
4 | 20 | 7.72 | 11.26 | 69% | < 0.001 | 61,0 |
4 | 40 | 7.72 | 11.26 | 69% | < 0.001 | 74,0 |
4 | 100 | 7.18 | 11.26 | 64% | < 0.001 | 70,2 |
5 | 5 | 18.83 | 18.49 | 102% | 0.91 | 46,3 |
5 | 20 | 16.41 | 18.49 | 89% | 0.055 | 42,3 |
5 | 100 | 15.18 | 18.49 | 82% | 0.005 | 37,6 |
6 | 20 | 9.02 | 15.32 | 59% | < 0.0001 | 49,5 |
6 | 40 | 7.98 | 15.32 | 52% | < 0.0001 | 51,0 |
6 | 100 | 7.54 | 15.32 | 49% | < 0.0001 | 52,0 |
3-OH-5,4'- dimethoxystilbene | ||||||
1 | 100 | 6.34 | 12.16 | 52% | < 0.0001 | 53,0 |
2 | 20 | 11.05 | 11.05 | 100% | 0.986 | 47,2 |
2 | 40 | 10.52 | 11.05 | 95% | 0.234 | 40,1 |
6 | 20 | 10.38 | 15.32 | 68% | < 0.0001 | 56,0 |
6 | 40 | 7.68 | 15.32 | 50% | < 0.0001 | 54,1 |
6 | 100 | 6.56 | 15.32 | 43% | < 0.0001 | 55,3 |
Pterostilbene | ||||||
1 | 100 | 9.55 | 12.16 | 79% | 0.005 | 69,9 |
4 | 20 | 10.43 | 11.26 | 93% | 0.336 | 54,0 |
4 | 40 | 10 | 11.26 | 89% | 0.035 | 65,1 |
4 | 100 | 8.07 | 11.26 | 72% | < 0.0001 | 51,1 |
6 | 20 | 13.72 | 15.32 | 90% | 0.058 | 55,1 |
6 | 40 | 14.41 | 15.32 | 94% | 0.142 | 51,4 |
6 | 100 | 10.98 | 15.32 | 72% | < 0.001 | 51,0 |
Desoxyrhapontigenin | ||||||
1 | 100 | 10.64 | 12.16 | 88% | 0.12 | 61,1 |
3 | 100 | 11.31 | 15.37 | 74% | < 0.0001 | 36,0 |
3 | 200 | 11.61 | 15.37 | 76% | < 0.0001 | 44,1 |
4 | 20 | 10.2 | 11.26 | 91% | 0.12 | 74,0 |
4 | 40 | 10.38 | 11.26 | 92% | 0.11 | 71,2 |
4 | 100 | 9.44 | 11.26 | 84% | 0.003 | 50,0 |
6 | 20 | 14.18 | 15.32 | 93% | 0.494 | 54,3 |
6 | 40 | 15.31 | 15.32 | 100% | 0.48 | 59,1 |
6 | 100 | 13.63 | 15.32 | 89% | 0.027 | 46,9 |
Pinostilbene | ||||||
1 | 100 | 13.6 | 12.16 | 112% | 0.062 | 68,1 |
2 | 20 | 10.04 | 11.05 | 91% | 0.266 | 55,0 |
2 | 40 | 11.53 | 11.05 | 104% | 0.319 | 42,5 |
3 | 100 | 16.9 | 15.37 | 110% | 0.448 | 41,0 |
3 | 200 | 15.23 | 15.37 | 99% | 0.411 | 42,5 |
6 | 20 | 14.24 | 15.32 | 93% | 0.319 | 56,3 |
6 | 40 | 17.33 | 15.32 | 113% | 0.085 | 60,0 |
6 | 100 | 16.24 | 15.32 | 106% | 0.724 | 51,2 |
Resveratrol | ||||||
1 | 100 | 12.18 | 12.16 | 100% | 0.867 | 70,3 |
2 | 20 | 11.85 | 11.05 | 107% | 0.182 | 48,4 |
2 | 40 | 10.53 | 11.05 | 95% | 0.924 | 55,0 |
3 | 100 | 16.64 | 15.37 | 108% | 0.435 | 30,4 |
3 | 200 | 17 | 15.37 | 111% | 0.337 | 38,0 |
6 | 20 | 14.65 | 15.32 | 96% | 0.804 | 54,5 |
6 | 40 | 16.17 | 15.32 | 106% | 0.501 | 59,0 |
6 | 100 | 17.55 | 15.32 | 115% | 0.055 | 58,0 |
Piceatannol | ||||||
2 | 20 | 11.72 | 11.05 | 106% | 0.362 | 44,0 |
2 | 40 | 11.58 | 11.05 | 105% | 0.5 | 37,9 |
3 | 100 | 17.78 | 15.37 | 116% | 0.094 | 55,1 |
3 | 200 | 17.5 | 15.37 | 114% | 0.166 | 55,1 |
6 | 20 | 13.71 | 15.32 | 89% | 0.231 | 50,1 |
6 | 40 | 15.63 | 15.32 | 102% | 0.75 | 50,1 |
6 | 100 | 16.6 | 15.32 | 108% | 0.146 | 50,1 |