From: Dibenzazecine compounds with a novel dopamine/5HT2A receptor profile and 3D-QSAR analysis
Compound | Ki-D1/Ki-D2 | Ki-D2/Ki-5HT2A |
---|---|---|
Haloperidol | 102 (100a)) | 0.02 (0.05a)) |
Clozapine | 0.83 (1.58a)) | 42.6 (19.95a)) |
LE400 | 2.09 | 9.12 |
LE410 | 0.60 | 7.24 |
LE420 | 0.56 | 21.4 |
LE300 | 0.16 | 294 |
LE403 | 0.03 | 93.5 |
LE404 | 0.04 | 49.0 |
RMI-81582 | 0.05a) | 31.6a) |
SCH23390 | 0.0004b) | 50.0c) |