Table 2 The influence of Pro and Raz on primary tumor of LLC (using Student T-test): Route: ip × 7 daily. Experiment term was 11 days. * P < 0.05 (treatment vs vehicle control). The numbers of mice were 30 for the control group and 20 for each treatment group. 100 % survival was observed in each group.
From: Antitumor effects of two bisdioxopiperazines against two experimental lung cancer models in vivo
Compounds | Dosage mg/kg/d | Body weight (g) | Tumor weight (g) | Tumor inhibition% |
|---|---|---|---|---|
Control | -- | 23.3/24.4 | 2.80 ± 0.04 | -- |
Razoxane | 20 | 23.3/23.4 | 1.61 ± 0.03* | 40.0 |
Probimane | 30 | 23.4/21.6 | 1.91 ± 0.03* | 32.1 |
Probimane | 60 | 23.3/23.8 | 1.80 ± 0.03* | 35.7 |