PDE inhibitor | PDE3 | PDE4 |
---|---|---|
EMD95833 | 33% inhibition at 3 μM | IC50 = 0.1 ± 0.004 μM |
EMD219906 | IC50 = 1.3 ± 0.06 μM | IC50 = 0.48 ± 0.03 μM |
EMD249615 | 39% inhibition at 3 μM | IC50 = 0.074 ± 0.004 μM |
EMD273316 | 46% inhibition at 3 μM | IC50 = 0.33 ± 0.01 μM |