BMC Pharmacology

Table 4 Effect of Carbenoxolone on muscle relaxant activity by traction test

From: Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice

Treatment	Dose	% failure
Normal saline	10 ml/kg	0
Diazepam	0.125 mg/kg	0
	0.25 mg/kg	50*
	0.5 mg/kg	100***
Carbenoxolone	200 mg/kg	20
	300 mg/kg	40
	400 mg/kg	60**

Carbenoxolone and diazepam (i.p.) were injected 60 and 30 minutes respectively, before the test. Values are the mean ± SEM for 10 mice, *P < 0.05, **P < 0.01, ***P < 0.001, Compared to control, Fisher's exact test (two sided)

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