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Table 5 Effects of the oral administration of Anethum graveolens seed aqueous extract and cimetidine on the pH and total gastric acid from pylorus-ligated mice

From: Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice

Treatment

Dose (g/kg)

pH

μEq H+

Saline

0.3 ml

3.37 ± 0.13

20.83 ± 2.04

Extract

0.05

3.59 ± 0.04***

12.50 ± 0***

Extract

0.18

3.65 ± 0.08***

12.50 ± 0***

Extract

0.32

3.83 ± 0.09***

10.41 ± 1.21***

Extract

0.45

4.45 ± 0.10***

5.41 ± 1.02***

Cimetidine

0.032

4.54 ± 0.11***

5.00 ± 0***

  1. Values are the mean ± S.E.M. of 6 mice, ***P < 0.001, Compared to control, Tukey-Kramer.