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Figure 6 | BMC Pharmacology

Figure 6

From: Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro

Figure 6

Concentration dependent effect of rasagiline, aminoindan or selegiline in the presence of single stimuli (SS) or theta burst stimuli (TBS) after stimulation of the metabotropic glutamate receptor by ACPD. Data are presented for the mean of n = 4 slices +- SEM. Statistically significant attenuation of pop-spike amplitude in comparison to ACPD-induced increases were obtained in the presence of 2.5 μM of rasagiline and aminoindan following single stimuli (SS) or theta burst stimulation. No effect was observed with selegiline. Stars indicate statistical significance of p < 0.05 in comparison to control.

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BMC Pharmacology

ISSN: 1471-2210