Figure 4

Selective in vivo inhibition of SalB on MMP-9 activity without down-regulating MMP-9 protein expression. (A) The representative zymogram for in vivo MMP-9 and MMP-2 enzymatic activities in each treatment group. (B) Quantification of data presented in Fig.4B, expressed as fold increase versus Sham. (C) Western blot analysis on MMP-9 expression in rats from each treatment group (upper panel). Same amount of protein loaded on each lane was verified by membrane stained with amino black (lower panel). (D) Quantification of data presented in Fig. 4C. Expression level of MMP-9 was expressed as fold increase versus Sham. n = 10 for each group. All of the values are expressed as mean ± S.E. *P < 0.05 versus Sham rats; #P < 0.05 versus MI rats.